Biologic Drugs for Crohn's Disease

Biologics are prescription drugs that target specific proteins in your body that cause inflammation. Your doctor may prescribe one if other treatments haven't worked.

The FDA has approved several biologic drugs for Crohn's: adalimumab, certolizumab, infliximab, natalizumab, risankizumab, ustekinumab, and vedolizumab. Each targets specific proteins involved in inflammation. Your doctor will give them in a shot or an IV.

Side effects of biologics can include reactions where the needle went in your skin, infections, and allergic reactions. The side effects vary based on the specific drug.

Biologic drugs, even generic versions, can be very expensive. They're hard to make and that drives up the price. One year of treatment can add up to about $20,000. Even if you have insurance, you may have to pay up to 35% of the cost.
 

Many drug companies and private groups offer programs that provide drugs at low or no cost. NeedyMeds can fill you in on more than 2,400 drug aid programs. RxAssist has a list of patient aid programs and drug discount cards. The Crohn's & Colitis Foundation of America can provide other resources.

Biologics target specific proteins in the inflammatory process, helping to reduce symptoms and achieve remission. Not everyone responds in the same way. Finding the most effective drug with the fewest side effects can take time.

Tell your doctor about all prescription and over-the-counter drugs, supplements, or natural remedies you take – and check with your doctor before you take anything new. Any of these can affect the way your medication works.